Zhejiang Chempharm Industry&Trading Co., Ltd

Product Name: (-)-Corey lactone diol

Synonym: (-) COREY LACTONE DIOL;(-)-COREY LACTONE DIOL,98%;(3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,;(1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone;(1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one;(3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one;(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98%;(+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one

MF: C8H12O4

MW: 172.18

Product Category: Latanoprost;Prostaglandins;API

Melting Point: 117-119 °C(lit.)

Boiling Point: 262.49°C (rough estimate)

Density: 1.2104 (rough estimate)

Refractive Index: 1.4455 (estimate)

Storage Temp.: -20°C

Form: Crystalline Powder or Crystals

pKa: 14.36±0.40(Predicted)

Color: White to beige-brown

Optical Activity: [α]20/D 44°, c = 1.4 in methanol

InChlKey: VYTZWRCSPHQSFX-GBNDHIKLSA-N

Safety Statements: 24/25

WGK Germany: 3

Chemical Property: white to beige-brown cryst. powder or crystals

Uses: (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmo nary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.